'Kill Me, Heal Me' narrates the story of Cha Do-hyun, a wealthy businessman, who is hiding his dissociative identity disorder from the world. On the other hand, Oh Ri-jin, a dedicated and determined first-year resident at a psychiatric hospital, covertly provides him with help with his condition to get better. Amid a secret love story that is stirring and the heavy burden of hiding profound secrets, they decide to hold hands and overcome their past and present challenges with each other’s support. For Do-hyun, the most important challenge is to have control over his own body. But, it becomes especially tough for him, when Oh Ri-jin's brother, Oh Ri-on, portrayed by Park Seo-joon, becomes suspicious of him and is determined to dig deep to uncover Do-hyun's secret. Often mistaken for a carefree person, Ri-on is, in reality, a well-known novelist, who keeps this side of him a secret, going by the name, Omega. The series is a binge-watch, brewing with sweetness and heartfelt moments. It thrives on the exceptional performances by the three actors. While the lead roles are of Cha Do-hyun and Oh Ri-jin, Seo-joon’s character shines through his remarkable charisma, adding a unique touch to the storyline.