A scientist in the Laser and Plasmatechnology division of Bombay’s Bhabha Atomic Research Institute, Thattey presses new-age Detective Holmes into service to uncover a national terrorist network. Holmes gets the police to cordon off the network but the terrorists can cross through. It turns out this is an internal agent who had crossed over. This may sound like a good potboiler but it exactly mirrors the discovery of prion or the disease-causing protein by Stanley Prusiner, which won him the 1997 Nobel Prize for Medicine. While conventional wisdom suggested that bacteria, virus and fungi caused disease and proteins were good for the body, Prusiner, tipped by the unexplained death of a patient, found that a protein with the wrong structure can cause disease. He said that proteins could be very similar but have positive or negative neurons. While positive neurons were good for the body, negative neurons could disrupt messages from reaching the brain or cause disease.