It is the biggest challenge for online education institutions and universities. The challenge lies not only in teaching and learning, but also in the emotional health and motivation of teachers and students. Maintaining self-motivation and maintaining students’ enthusiasm is a big challenge. Isolation without much interaction with the outside world is a psychological factor that still has a great impact on the enthusiasm of teachers and students. Data security and privacy issues are other challenges that need to be resolved at the individual and organizational levels. Network-related issues are very high, and data security and user privacy are greatly threatened. These challenges will decrease in the future, but from now on, they are of great concern to everyone. In the coming era, there will be new opportunities, and the ever-changing world will see new standards for online teaching. Together, we can realize the transition from classroom to blended learning mode as the most effective method in the education system.