When she was 22, Gita Ramanan stepped into a meeting room where 18 men were seated. “When is your boss coming?” one of them asked. Having recently been selected from among 150 architects for a competition to design a complex of 800 apartments, she gently broke it to them that she was in charge. Thirteen years later, she still reigns as the boss—at Design Cafe, an interiors firm with more than 700 employees and 5,000 clients that she set up with her partner Shezan Bhojani.