Normally, dietary sodium intake is restricted to 2000-4000 mg/d for patients with CKD to control hypertension, and to avoid excessive thirst and fluid consumption in patients with oliguria or anuria. Salt substitutes frequently contain potassium chloride, and patients should be instructed to avoid salt substitutes as they can precipitate hyperkalemia. In most nondialyzed patients with advanced renal failure, a daily intake of 1000-3000 mg (40-130 mEq) of sodium and 1500-3000 mL of fluid will maintain sodium and water balance. The requirement for sodium and water varies markedly, and each patient must be managed on an individual basis.