With the outbreak of the coronavirus pandemic or COVID-19, initially much emphasis was laid on the elderly people, specifically those with other pre-existing health ailments such as obesity, hypertension, and diabetes are at a high risk of contracting and/or succumbing to COVID-19. But now it is coming into picture that gender difference is also one of the factors. The epidemiological findings postulated across different parts of the world indicated higher morbidity and mortality in males than females. The possible reasons are –