Aston Villa's clash with Newcastle United has become the first Premier League match this season to be postponed due to a coronavirus outbreak within one of the teams. (More Football News)
Newcastle say there are "several" players and staff members self-isolating after returning positive tests in recent days.
The club's training ground has been closed in an effort to contain the outbreak, which has hampered the squad's ability to train and prepare for Friday's game at Villa Park.
Newcastle lodged a request with the Premier League to have the game moved, which was accepted on Tuesday.
In a statement, the Premier League Board said it agreed that Newcastle were "unable to train and adequately and safely prepare for their match on Friday".
The statement added: "The decision has been taken in consultation with Newcastle United and Aston Villa, and following extensive consultation with PHE [Public Health England] and Premier League medical advisors, with the health of players and staff the priority.
"All players and training ground staff will be re-tested this week and another meeting between the club, PHE and the Premier League will take place to assess the test results.
"The Premier League wishes those with COVID-19 a safe and speedy recovery and will rearrange the postponed fixture against Aston Villa in due course."
Newcastle said: "The match, which was set to kick off at 8pm (GMT) on Friday evening, will now be rescheduled and a new date and time will be confirmed in due course. Newcastle United would like to thank Aston Villa Football Club for its understanding.
"Newcastle United was one of the first clubs in the country to close its training ground prior to the first national lockdown in March and the club introduced comprehensive COVID-19 protocols in line with Premier League and government guidance to protect its players and staff ahead of Project Restart.
"While the club has continued to ensure strict adherence to these protocols, and despite previously experiencing only a very small number of isolated COVID-19 cases, positive test results have risen sharply in recent days."
Newcastle are 13th in the table, a point behind Aston Villa, who have played a game less.
